TECENTRIQ® (atezolizumab) injection
IMPORTANT FACTS ABOUT TECENTRIQ
The information provided here is not
comprehensive. To learn more, talk to your
healthcare provider (HCP).
Call 1 (844) TECENTRIQ (832-3687)
or go to TECENTRIQ.com to get FDA-approved
product labeling, including Medication Guide.
What is the most important information
I should know about TECENTRIQ?
• TECEN TRIQ is a medicine that may treat your
bladder cancer by working with your immune
system. TECENTRIQ can cause your immune
system to attack normal organs and tissues
in many areas of your body and can affect the
way they work. These problems can sometimes
become serious or life threatening and can lead
Call or see your HCP right away if you get any
symptoms of the following problems or these
symptoms get worse:
• Lung problems (pneumonitis). Signs and
symptoms may include: new or worsening
cough, shortness of breath, chest pain.
• Liver problems (hepatitis). Signs and
symptoms may include: yellowing of your skin
or the whites of your eyes, severe nausea or
vomiting, pain on the right side of your stomach
area (abdomen), drowsiness, dark urine (tea
colored), bleeding or bruising more easily
than normal, feeling less hungry than usual.
• Intestinal problems (colitis). Signs and
symptoms may include: diarrhea (loose stools)
or more bowel movements than usual, blood in
your stools or dark, tarry, sticky stools, severe
stomach area (abdomen) pain or tenderness.
• Hormone gland problems (especially the
pituitary, thyroid, adrenal glands, and
pancreas). Signs and symptoms may include:
headaches that will not go away or unusual
headaches, extreme tiredness, weight gain or
weight loss, dizziness or fainting, feeling more
hungry or thirsty than usual, hair loss, changes
in mood or behavior (such as decreased sex
drive, irritability, or forgetfulness), feeling cold,
constipation, your voice gets deeper, urinating
more often than usual, nausea or vomiting,
stomach area (abdomen) pain.
• Nervous system problems (neuropathy,
meningitis, encephalitis). Signs and symptoms
may include: severe muscle weakness,
numbness or tingling in hands or feet, fever,
confusion, changes in mood or behavior,
extreme sensitivity to light, neck stiffness.
• Inflammation of the eyes. Signs and symptoms
may include: blurry vision, double vision, or other
vision problems, eye pain or redness.
• Severe infections. Signs and symptoms may
include: fever, cough, frequent urination, flu-like
symptoms, pain when urinating.
• Severe infusion reactions. Signs and
symptoms may include: chills or shaking,
itching or rash, flushing, shortness of breath or
wheezing, dizziness, fever, feeling like passing
out, back or neck pain, swelling of your face
Getting medical treatment right away may
help keep these problems from becoming
Your HCP will check you for these problems
during your treatment with TECEN TRIQ. Your HCP
may treat you with corticosteroid or hormone
replacement medicines. Your HCP may delay or
completely stop treatment with TECEN TRIQ if you
have severe side effects.
What is TECENTRIQ?
TECENTRIQ is a prescription medicine used
• a type of bladder cancer called urothelial
carcinoma. TECENTRIQ may be used when
your bladder cancer has spread or cannot
be removed by surgery (advanced urothelial
• you have tried chemotherapy that contains
platinum, and it did not work or is no longer
It is not known if TECENTRIQ is safe and effective
in children. The approval of TECENTRIQ in these
patients is based on a study that measured
response rate and duration of response. There is
an ongoing study to confirm clinical benefit.
What should I tell my HCP before
Before you receive TECENTRIQ, tell your HCP
about all of your medical conditions, including
• have immune system problems such as Crohn’s
disease, ulcerative colitis, or lupus
• have had an organ transplant
• have lung or breathing problems
• have liver problems
• have a condition that affects your nervous
system, such as myasthenia gravis or
• are being treated for an infection
• are pregnant or plan to become pregnant.
TECENTRIQ can harm your unborn baby. If you
are able to become pregnant, you should use an
effective method of birth control during your
treatment and for at least 5 months after the
last dose of TECENTRIQ.
• are breastfeeding or plan to breastfeed. It is
not known if TECENTRIQ passes into your breast
milk. Do not breastfeed during treatment and
for at least 5 months after the last dose of
Tell your HCP about all the medicines you take,
including prescription and over-the-counter
medicines, vitamins, and herbal supplements.
How will I receive TECENTRIQ?
• Your HCP will give you TECENTRIQ into your
vein through an intravenous (IV) line over
30 to 60 minutes.
• TECEN TRIQ is usually given every 3 weeks.
• Your HCP will decide how many treatments
• Your HCP will test your blood to check you
for certain side effects.
• If you miss any appointments, call your
HCP as soon as possible to reschedule
What are the possible side effects
TECENTRIQ can cause serious side effects,
• See “What is the most important
information I should know about
The most common side effects of TECENTRIQ
in urothelial carcinoma include: feeling tired,
decreased appetite, nausea, urinary tract
infection, fever, constipation.
TECENTRIQ may cause fertility problems in
females, which may affect the ability to have
children. Talk to your HCP if you have concerns
These are not all the possible side effects of
TECENTRIQ. Ask your HCP or pharmacist for more
information. Call your doctor for medical advice
about side effects. You may report side effects to
the FDA at 1-800-FDA-1088.
TECENTRIQ is a registered trademark of Genentech, Inc.
U. S. License No. 1048 Issued: October 2016
© 2016 Genentech USA, Inc. All rights reserved.
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