usual, nausea or vomiting, and stomach area
• Nervous system problems (neuropathy,
meningitis, encephalitis)—signs and
symptoms of nervous system problems may
include severe muscle weakness, numbness
or tingling in hands and feet, fever, confusion,
changes in mood or behavior, extreme
sensitivity to light, and neck stiffness
• Inflammation of the eyes—signs and
symptoms may include blurry vision, double
vision, or other vision problems, and eye pain
• Severe infections—signs and symptoms of
infection may include fever, cough, frequent
urination, flu-like symptoms, and pain
• Severe infusion reactions—signs and
symptoms of infusion reactions may include
chills or shaking, itching or rash, flushing,
shortness of breath or wheezing, dizziness,
fever, feeling like passing out, back or neck
pain, and swelling of your
face or lips
Before you receive TECENTRIQ, tell your
healthcare provider about all your medical
conditions, including if you:
• Have immune system problems (such as
Crohn’s disease, ulcerative colitis, or lupus);
have had an organ transplant; have lung or
breathing problems; have liver problems;
have a condition that affects your nervous
system (such as myasthenia gravis or Guillain-Barré syndrome); or are being treated for an
• Are pregnant or plan to become pregnant
– TECENTRIQ can harm your unborn baby
– If you are able to become pregnant, you
should use an effective method of birth
control during your treatment and for
at least 5 months after the last dose of
• Are breastfeeding or plan to breastfeed
– It is not known if TECENTRIQ passes into
your breast milk
– Do not breastfeed during treatment and
for at least 5 months after the last dose of
Tell your healthcare provider about all the
medicines you take, including prescription
and over-the-counter medicines, vitamins, and
The most common side effects of TECENTRIQ
in people with urothelial carcinoma include:
• Feeling tired
• Decreased appetite
• Urinary tract infection
TECENTRIQ may cause fertility problems in
females, which may affect the ability to have
children. Talk to your healthcare provider if you
have concerns about fertility.
These are not all the possible side effects of
TECENTRIQ. Ask your healthcare provider or
pharmacist for more information.
You may report side effects to the FDA
at 1-800-FDA-1088 or www.fda.gov/medwatch.
You may also report side effects to Genentech at
Please see Summary of Medication Guide on
the following page.
Ask your doctor about TECENTRIQ, given once every 3 weeks† as an intravenous infusion‡.
© 2017 Genentech USA, Inc. All rights reserved.
PDL/022316/0028( 1) Printed in USA.
† A 60-minute initial infusion and, if tolerated, a 30-minute treatment every 3 weeks.
‡ Your healthcare provider will give you TECENTRIQ into your vein through an intravenous (IV) line over 30-60 minutes.
A path forward