TECENTRIQ® (atezolizumab) injection
IMPORTANT FACTS ABOUT TECENTRIQ
The information provided here is not
comprehensive. To learn more, talk to your
healthcare provider (HCP).
Call 1 (877) GENENTECH (436-3683) or go to
TECENTRIQ.com to get FDA-approved product
labeling, including Medication Guide.
What is the most important
information I should know about
• TECENTRIQ is a medicine that may treat a type
of lung cancer by working with your immune
system. TECENTRIQ can cause your immune
system to attack normal organs and tissues
and can affect the way they work. These
problems can sometimes become serious or
life-threatening and can lead to death.
Call or see your HCP right away if you get any
symptoms of the following problems or these
symptoms get worse:
• Lung problems (pneumonitis). Signs and
symptoms may include: new or worsening
cough, shortness of breath, chest pain.
• Liver problems (hepatitis). Signs and
symptoms may include: yellowing of your skin
or the whites of your eyes, severe nausea or
vomiting, pain on the right side of your stomach
area (abdomen), drowsiness, dark urine (tea
colored), bleeding or bruising more easily than
normal, feeling less hungry than usual.
• Intestinal problems (colitis). Signs and
symptoms may include: diarrhea (loose stools)
or more bowel movements than usual, blood
or mucous in your stools or dark, tarry, sticky
stools, severe stomach area (abdomen) pain
• Hormone gland problems (especially the
thyroid, adrenal glands, pancreas, and
pituitary). Signs and symptoms may include:
headaches that will not go away or unusual
headaches, extreme tiredness, weight gain or
weight loss, dizziness or fainting, feeling more
hungry or thirsty than usual, hair loss, changes
in mood or behavior, such as decreased sex
drive, irritability, or forgetfulness, feeling cold,
constipation, your voice gets deeper, urinating
more often than usual, nausea or vomiting,
stomach area (abdomen) pain.
• Problems in other organs. Signs and
symptoms may include: severe muscle
weakness, numbness or tingling in hands or
feet, confusion, blurry vision, double vision,
or other vision problems, changes in mood
or behavior, extreme sensitivity to light, neck
stiffness, eye pain or redness, skin blisters
or peeling, chest pain, irregular heartbeat,
shortness of breath or swelling of the ankles.
• Severe infections. Signs and symptoms may
include: fever, cough, flu-like symptoms, pain
when urinating, frequent urination or swelling
of the ankles.
• Severe infusion reactions. Signs and
symptoms may include: chills or shaking,
itching or rash, flushing, shortness of breath
or wheezing, swelling of your face or lips,
dizziness, fever, feeling like passing out, back
or neck pain.
Getting medical treatment right away may
help keep these problems from becoming
Your HCP will check you for these problems
during your treatment with TECENTRIQ. Your HCP
may treat you with corticosteroid or hormone
replacement medicines. Your HCP may delay or
completely stop treatment with TECEN TRIQ if you
have severe side effects.
What is TECENTRIQ?
TECENTRIQ is a prescription medicine used to treat:
a type of lung cancer called non-small cell
lung cancer (NSCLC).
TECENTRIQ may be used when your lung cancer:
– has spread or grown, and
– you have tried chemotherapy that
contains platinum, and it did not work or is
no longer working.
If your tumor has an abnormal EGFR or ALK
gene, you should have also tried an FDA-approved therapy for tumors with these
abnormal genes, and it did not work or is
no longer working.
It is not known if TECENTRIQ is safe and
effective in children.
What should I tell my HCP before
Before you receive TECENTRIQ, tell your HCP
about all of your medical conditions,
including if you:
• have immune system problems such as Crohn’s
disease, ulcerative colitis, or lupus
• have had an organ transplant
• have lung or breathing problems
• have liver problems
• have a condition that affects your nervous
system, such as myasthenia gravis or Guillain-Barré syndrome
• are being treated for an infection
• are pregnant or plan to become pregnant.
TECENTRIQ can harm your unborn baby. Tell
your HCP right away if you become pregnant or
think you may be pregnant during treatment
If you are able to become pregnant:
– Your HCP should do a pregnancy test before
you start treatment with TECEN TRIQ.
– You should use an effective method of
birth control during your treatment and
for at least 5 months after the last dose of
• are breastfeeding or plan to breastfeed. It is not
known if TECENTRIQ passes into your breast milk.
Do not breastfeed during treatment and for at
least 5 months after the last dose of TECENTRIQ.
Tell your HCP about all the medicines you
take, including prescription and over-the-counter
medicines, vitamins, and herbal supplements.
How will I receive TECENTRIQ?
• Your HCP will give you TECENTRIQ into your
vein through an intravenous (IV) line over
30 to 60 minutes.
• TECEN TRIQ is usually given every 3 weeks.
• Your HCP will decide how many treatments
• Your HCP will test your blood to check you for
certain side effects.
• If you miss any appointments, call your
HCP as soon as possible to reschedule
What are the possible side effects of
TECENTRIQ can cause serious side effects,
• See “What is the most important information
I should know about TECENTRIQ?”
The most common side effects of TECENTRIQ in
people with NSCLC include: feeling tired, decreased
appetite, muscle pain, cough, shortness of breath.
TECEN TRIQ may cause fertility problems in
females, which may affect the ability to have
children. Talk to your HCP if you have concerns
These are not all the possible side effects of
TECEN TRIQ. Ask your HCP or pharmacist for more
information. Call your doctor for medical advice
about side effects. You may report side effects to
the FDA at 1-800-FDA-1088.
TECEN TRIQ is a registered trademark of Genentech, Inc.
U.S. License No. 1048 Issued: April 2018
© 2018 Genentech USA, Inc. All rights reserved.
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